Ch55-O-C3-NH2


Catalog No. Size PriceQuantity
M11591-2 contact sales@xcessbio.com $7,000
M11591-10 contact sales@xcessbio.com $7,000

Description

Ch55-O-C3-NH2 (RAR ligand 1) is a Ch 55-based ligand, which targets RAR. Ch55-O-C3-NH2 (RAR ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER.

Product information

CAS Number: 144298-98-6

Molecular Weight: 437.57

Formula: C27H35NO4

Synonym:

RAR ligand 1

Chemical Name: 2-(3-aminopropoxy)-4-[(1E)-3-(3, 5-di-tert-butylphenyl)-3-oxoprop-1-en-1-yl]benzoic acid

Smiles: CC(C)(C)C1C=C(C=C(C=1)C(C)(C)C)C(=O)/C=C/C1=CC(OCCCN)=C(C=C1)C(O)=O

InChiKey: SCMXMXZHZNYFOT-PKNBQFBNSA-N

InChi: InChI=1S/C27H35NO4/c1-26(2,3)20-15-19(16-21(17-20)27(4,5)6)23(29)11-9-18-8-10-22(25(30)31)24(14-18)32-13-7-12-28/h8-11,14-17H,7,12-13,28H2,1-6H3,(H,30,31)/b11-9+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

Products are for research use only. Not for human use.

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