(S,R,S)-AHPC-Me-C7 ester

Catalog No. Size PriceQuantity
M11613-2 Contact sales@xcessbio.com for quotation $100
M11613-10 Contact sales@xcessbio.com for quotation $100


(S, R, S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders.

Product information

Molecular Weight: 614.80

Formula: C32H46N4O6S

Chemical Name: ethyl 6-{[(2S)-1-[(2S, 4R)-4-hydroxy-2-{[(1S)-1-[4-(4-methyl-1, 3-thiazol-5-yl)phenyl]ethyl]carbamoyl}pyrrolidin-1-yl]-3, 3-dimethyl-1-oxobutan-2-yl]carbamoyl}hexanoate

Smiles: CC1N=CSC=1C1C=CC(=CC=1)[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCC(=O)OCC)C(C)(C)C


InChi: InChI=1S/C32H46N4O6S/c1-7-42-27(39)12-10-8-9-11-26(38)35-29(32(4,5)6)31(41)36-18-24(37)17-25(36)30(40)34-20(2)22-13-15-23(16-14-22)28-21(3)33-19-43-28/h13-16,19-20,24-25,29,37H,7-12,17-18H2,1-6H3,(H,34,40)(H,35,38)/t20-,24+,25-,29+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.

Products are for research use only. Not for human use.

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