Ac4ManNAz


Catalog No. Size PriceQuantity
M11635-2 2mg solid $120
M11635-10 10mg solid $360

Description

Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 361154-30-5

Molecular Weight: 430.37

Formula: C16H22N4O10

Chemical Name: [(2R, 3S, 4R, 5S)-3, 4, 6-tris(acetyloxy)-5-(2-azidoacetamido)oxan-2-yl]methyl acetate

Smiles: CC(=O)O[C@H]1[C@H](OC(C)=O)[C@H](NC(=O)CN=[N+]=[N-])C(O[C@@H]1COC(C)=O)OC(C)=O

InChiKey: HGMISDAXLUIXKM-LIADDWGISA-N

InChi: InChI=1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13+,14-,15-,16?/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (232.36 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Products are for research use only. Not for human use.

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