Boc-C5-O-C5-O-C6-Cl


Catalog No. Size PriceQuantity
M11652-2 2mg solid $95
M11652-10 10mg solid $285

Description

Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.

Product information

CAS Number: 1835705-52-6

Molecular Weight: 393.00

Formula: C21H41ClO4

Synonym:

PROTAC Linker 2

Chemical Name: tert-butyl 6-({5-[(6-chlorohexyl)oxy]pentyl}oxy)hexanoate

Smiles: CC(C)(C)OC(=O)CCCCCOCCCCCOCCCCCCCl

InChiKey: BCFCLXINSZPNKH-UHFFFAOYSA-N

InChi: InChI=1S/C21H41ClO4/c1-21(2,3)26-20(23)14-8-6-11-17-25-19-13-7-12-18-24-16-10-5-4-9-15-22/h4-19H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10.
  2. ARYL SULFONOHYDRAZIDES. US 20170121321 A1.

Products are for research use only. Not for human use.

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