Catalog No. Size PriceQuantity
M11690-2 2mg solid $150
M11690-10 10mg solid $460


UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13  nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.

Product information

CAS Number: 1515888-53-5

Molecular Weight: 423.51

Formula: C26H25N5O

Chemical Name: (1-(2, 5-dimethylbenzyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-2-yl)(pyridin-4-yl)methanol

Smiles: CN1C=C(C=N1)C1=CC2=C(C=C1)N=C(C(O)C1C=CN=CC=1)N2CC1=CC(C)=CC=C1C


InChi: InChI=1S/C26H25N5O/c1-17-4-5-18(2)21(12-17)16-31-24-13-20(22-14-28-30(3)15-22)6-7-23(24)29-26(31)25(32)19-8-10-27-11-9-19/h4-15,25,32H,16H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 85 mg/mL(200.7 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. James O'Connell, et al. Nat Commun. 2019 Dec 19;10(1):5795.

Products are for research use only. Not for human use.

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