Description
TMCB is a selective, ATP-competitive CK2 (casein kinase II) inhibitor with distinct Ki values of 83 nM and 21 nM for the two different catalytic CK2 subunits α and α', respectively.
Product information
CAS Number: 905105-89-7
Molecular Weight: 534.82
Formula: C11H9Br4N3O2
Chemical Name: N-(2, 3, 5, 6-tetrabromo-4-methoxyphenyl)-4, 5-dihydro-1H-imidazole-2-carboxamide
Smiles: COC1C(Br)=C(Br)C(NC(=O)C2NCCN=2)=C(Br)C=1Br
InChiKey: AFQUQOBKQLLGLK-UHFFFAOYSA-N
InChi: InChI=1S/C11H9Br4N3O2/c1-20-9-6(14)4(12)8(5(13)7(9)15)18-11(19)10-16-2-3-17-10/h2-3H2,1H3,(H,16,17)(H,18,19)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Bollacke A, Nienberg C, Borgne ML, Jose J. Toward selective CK2alpha and CK2alpha' inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha'. J Pharm Biomed Anal. 2016;121:253-260.
Products are for research use only. Not for human use.
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