(E/Z)-AG490


Catalog No. Size PriceQuantity
M11713-2 2mg solid $205
M11713-10 10mg solid $715

Description

(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.

Product information

CAS Number: 134036-52-5

Molecular Weight: 294.30

Formula: C17H14N2O3

Synonym:

(E/Z)-Tyrphostin AG490

(E/Z)-Tyrphostin B42

Chemical Name: (E/Z)-N-benzyl-2-cyano-3-(3, 4-dihydroxyphenyl)acrylamide

Smiles: N#CC(=CC1=CC(O)=C(O)C=C1)C(=O)NCC1C=CC=CC=1

InChiKey: TUCIOBMMDDOEMM-RIYZIHGNSA-N

InChi: InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 58 mg/mL(197.07 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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