Catalog No. Size PriceQuantity
M11732-2 Contact for quotation $100
M11732-10 Contact for quotation $100


AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.

Product information

CAS Number: 2228908-91-4

Molecular Weight: 385.48

Formula: C20H28FN7

Chemical Name: N4-[(2R)-butan-2-yl]-N2-{2-fluoro-5-[(1S, 4S)-5-methyl-2, 5-diazabicyclo[2.2.1]heptan-2-yl]pyridin-3-yl}-5-methylpyrimidine-2, 4-diamine

Smiles: CN1C[C@@H]2C[C@H]1CN2C1=CN=C(F)C(=C1)NC1=NC(N[C@H](C)CC)=C(C)C=N1


InChi: InChI=1S/C20H28FN7/c1-5-13(3)24-19-12(2)8-23-20(26-19)25-17-7-14(9-22-18(17)21)28-11-15-6-16(28)10-27(15)4/h7-9,13,15-16H,5-6,10-11H2,1-4H3,(H2,23,24,25,26)/t13-,15+,16+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Grimster NP, et al. Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors. J Med Chem. 2018 Jun 28;61(12):5235-5244.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed