AG126


Catalog No. Size PriceQuantity
M11777-2 2mg solid $110
M11777-10 10mg solid $330

Description

AG126 is a tyrosine kinase inhibitor which can prevent the activation of mitogen-activated protein kinase p42MAPK (ERK2).

Product information

CAS Number: 118409-62-4

Molecular Weight: 215.17

Formula: C10H5N3O3

Synonym:

Tyrphostin AG126

Chemical Name: 2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile

Smiles: N#CC(=CC1=CC(O)=C(C=C1)[N+]([O-])=O)C#N

InChiKey: DUQADSPERJRQBW-UHFFFAOYSA-N

InChi: InChI=1S/C10H5N3O3/c11-5-8(6-12)3-7-1-2-9(13(15)16)10(14)4-7/h1-4,14H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (464.75 mM; Need ultrasonic and warming)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Cuzzocrea S, et al. The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation. Am J Pathol. 2000 Jul;157(1):145-58.

Products are for research use only. Not for human use.

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