Catalog No. Size PriceQuantity
M12079-2 Contact for quotation $100
M12079-10 Contact for quotation $100


SMU-C80 (EC50 = 31.02 ± 1.01 nM) is a TLR2-specific agonist. Mechanistic studies revealed that SMU-C80, through TLR1/2, recruits the adaptor protein MyD88 and triggers the NF-κB pathway to release cytokines such as TNF-α and IL-1β from human, but not murine, cells.

Product information

Molecular Weight: 428.54

Formula: C22H21FN2O2S2

Chemical Name: isopropyl 2-(3-(4-fluoronaphthalen-1-yl)thioureido)-5, 6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate

Smiles: CC(C)OC(=O)C1=C(NC(=S)NC2=CC=C(F)C3=CC=CC=C23)SC2CCCC=21


InChi: InChI=1S/C22H21FN2O2S2/c1-12(2)27-21(26)19-15-8-5-9-18(15)29-20(19)25-22(28)24-17-11-10-16(23)13-6-3-4-7-14(13)17/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H2,24,25,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed