SMU-C80


Catalog No. Size PriceQuantity
M12079-2 Contact sales@xcessbio.com for quotation $100
M12079-10 Contact sales@xcessbio.com for quotation $100

Description

SMU-C80 (EC50 = 31.02 ± 1.01 nM) is a TLR2-specific agonist. Mechanistic studies revealed that SMU-C80, through TLR1/2, recruits the adaptor protein MyD88 and triggers the NF-κB pathway to release cytokines such as TNF-α and IL-1β from human, but not murine, cells.

Product information

Molecular Weight: 428.54

Formula: C22H21FN2O2S2

Chemical Name: isopropyl 2-(3-(4-fluoronaphthalen-1-yl)thioureido)-5, 6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate

Smiles: CC(C)OC(=O)C1=C(NC(=S)NC2=CC=C(F)C3=CC=CC=C23)SC2CCCC=21

InChiKey: DPIZCURGUHTZEV-UHFFFAOYSA-N

InChi: InChI=1S/C22H21FN2O2S2/c1-12(2)27-21(26)19-15-8-5-9-18(15)29-20(19)25-22(28)24-17-11-10-16(23)13-6-3-4-7-14(13)17/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H2,24,25,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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