(S, R, S)-AHPC-Me is the (S, R, S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S, R, S)-AHPC-Me can be used to synthesize ARV-771, a BET PROTAC degrader.
CAS Number: 1948273-02-6
Molecular Weight: 444.59
VHL ligand 2
E3 ligase Ligand 1A
Chemical Name: (2S, 4R)-1-[(2S)-2-amino-3, 3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1, 3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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