Description
Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) .
Product information
CAS Number: 108657-10-9
Molecular Weight: 362.42
Formula: C20H26O6
Chemical Name: (3aR, 4R, 9S, 11aR)-9-hydroxy-6, 10-dimethyl-3-methylidene-2-oxo-2H, 3H, 3aH, 4H, 5H, 8H, 9H, 11aH-cyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methylbut-2-enoate
Smiles: C/C(=C\CO)/C(=O)O[C@@H]1CC(C)=CC[C@H](O)C(C)=C[C@H]2OC(=O)C(=C)[C@@H]21 |c:11,17|
InChiKey: APOGLVUGPAVNAP-NMSLRBGTSA-N
InChi: InChI=1S/C20H26O6/c1-11-5-6-15(22)13(3)10-17-18(14(4)20(24)26-17)16(9-11)25-19(23)12(2)7-8-21/h5,7,10,15-18,21-22H,4,6,8-9H2,1-3H3/b11-5-,12-7+,13-10-/t15-,16+,17+,18+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Yang B, , et al. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.