Duocarmycin TM


Catalog No. Size PriceQuantity
M12131-2 2mg solid $245
M12131-10 10mg solid $920

Description

Duocarmycin TM is an exceptionally potent antitumor antibiotic. Duocarmycin TM is a DNA alkylator.

Product information

CAS Number: 157922-77-5

Molecular Weight: 466.91

Formula: C25H23ClN2O5

Chemical Name: (1S)-1-(chloromethyl)-3-(5, 6, 7-trimethoxy-1H-indole-2-carbonyl)-1H, 2H, 3H-benzo[e]indol-5-ol

Smiles: COC1=CC2C=C(NC=2C(OC)=C1OC)C(=O)N1C[C@@H](CCl)C2C1=CC(O)=C1C=CC=CC1=2

InChiKey: NRHDGIYFJJUFKN-CQSZACIVSA-N

InChi: InChI=1S/C25H23ClN2O5/c1-31-20-9-13-8-17(27-22(13)24(33-3)23(20)32-2)25(30)28-12-14(11-26)21-16-7-5-4-6-15(16)19(29)10-18(21)28/h4-10,14,27,29H,11-12H2,1-3H3/t14-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 50 mg/mL (107.09 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Dale L. Boger, et al. Critical Role of the Linking Amide in CC-1065 and the Duocarmycins: Implications on the Source of DNA Alkylation Catalysis. J. Am. Chem. Soc. 1998, 120, 11554-11557.

Products are for research use only. Not for human use.

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