(S)-Seco-Duocarmycin SA

Catalog No. Size PriceQuantity
M12138-2 2mg solid $1,490
M12138-10 10mg solid $5,960


(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates.

Product information

CAS Number: 152785-82-5

Molecular Weight: 513.93

Formula: C25H24ClN3O7

Chemical Name: methyl (8S)-8-(chloromethyl)-4-hydroxy-6-(5, 6, 7-trimethoxy-1H-indole-2-carbonyl)-3H, 6H, 7H, 8H-pyrrolo[3, 2-e]indole-2-carboxylate

Smiles: COC1=C(OC)C2NC(=CC=2C=C1OC)C(=O)N1C[C@@H](CCl)C2C1=CC(O)=C1NC(=CC=21)C(=O)OC


InChi: InChI=1S/C25H24ClN3O7/c1-33-18-6-11-5-14(27-20(11)23(35-3)22(18)34-2)24(31)29-10-12(9-26)19-13-7-15(25(32)36-4)28-21(13)17(30)8-16(19)29/h5-8,12,27-28,30H,9-10H2,1-4H3/t12-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.

Products are for research use only. Not for human use.

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