(+)-CBI-CDPI1


Catalog No. Size PriceQuantity
M12161-2 Contact sales@xcessbio.com for price quotation $100
M12161-10 Contact sales@xcessbio.com for price quotation $100

Description

(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI1 is an antibody drug conjugates (ADCs) toxin.

Product information

CAS Number: 128300-14-1

Molecular Weight: 424.45

Formula: C25H20N4O3

Chemical Name: 7-[(1R, 13S)-8-oxo-11-azatetracyclo[8.4.0.0, .0, ]tetradeca-2, 4, 6, 9-tetraene-11-carbonyl]-1H, 2H, 3H, 6H-pyrrolo[3, 2-e]indole-3-carboxamide

Smiles: NC(=O)N1CCC2C1=CC=C1NC(=CC=21)C(=O)N1C[C@H]2C[C@]32C1=CC(=O)C1=CC=CC=C31

InChiKey: ZYNHKKZUGALOOV-YMXBGEKHSA-N

InChi: InChI=1S/C25H20N4O3/c26-24(32)28-8-7-14-16-9-19(27-18(16)5-6-20(14)28)23(31)29-12-13-11-25(13)17-4-2-1-3-15(17)21(30)10-22(25)29/h1-6,9-10,13,27H,7-8,11-12H2,(H2,26,32)/t13-,25-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed