17-GMB-APA-GA


Catalog No. Size PriceQuantity
M12171-2 Contact sales@xcessbio.com for quotation $100
M12171-10 Contact sales@xcessbio.com for quotation $100

Description

17-GMB-APA-GA is an ADC Cytotoxin. 17-GMB-APA-GA is a potent HSP90 inhibitor and used for latent T. gondii infection research.

Product information

CAS Number: 256337-10-7

Molecular Weight: 767.87

Formula: C39H53N5O11

Chemical Name: (8S, 9S, 12S, 13R, 14S, 16R)-19-({3-[4-(2, 5-dioxo-2, 5-dihydro-1H-pyrrol-1-yl)butanamido]propyl}amino)-13-hydroxy-8, 14-dimethoxy-4, 10, 12, 16-tetramethyl-3, 20, 22-trioxo-2-azabicyclo[16.3.1]docosa-1(21), 4, 6, 10, 18-pentaen-9-yl carbamate

Smiles: CC1=C[C@H](C)[C@@H](O)[C@H](C[C@H](C)CC2=C(NCCCNC(=O)CCCN3C(=O)C=CC3=O)C(=O)C=C(NC(=O)C(C)=CC=C[C@H](OC)[C@H]1OC(N)=O)C2=O)OC |c:1,42,t:40|

InChiKey: OPWAYYOLUIAKCJ-GQHIRADRSA-N

InChi: InChI=1S/C39H53N5O11/c1-22-18-26-34(42-16-9-15-41-31(46)12-8-17-44-32(47)13-14-33(44)48)28(45)21-27(36(26)50)43-38(51)23(2)10-7-11-29(53-5)37(55-39(40)52)25(4)20-24(3)35(49)30(19-22)54-6/h7,10-11,13-14,20-22,24,29-30,35,37,42,49H,8-9,12,15-19H2,1-6H3,(H2,40,52)(H,41,46)(H,43,51)/b11-7-,23-10-,25-20-/t22-,24+,29+,30+,35-,37+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Sergio O Angel, et al. A Review of Recent Patents on the Protozoan Parasite HSP90 as a Drug Target. Recent Pat Biotechnol. 2013 Apr;7(1):2-8.

Products are for research use only. Not for human use.

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