Erlotinib D6 hydrochloride


Catalog No. Size PriceQuantity
M12237-2 Contact sales@xcessbio.com for quotation $100
M12237-10 Contact sales@xcessbio.com for quotation $100

Description

Erlotinib D6 hydrochloride (CP-358774 D6 hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM.

Product information

CAS Number: 1189953-78-3

Molecular Weight: 435.93

Formula: C22H24ClN3O4

Synonym:

CP-358774 D6 hydrochloride

NSC 718781 D6 hydrochloride

OSI-774 D6 hydrochloride

Chemical Name: N-(3-ethynylphenyl)-6, 7-bis[2-(H)methoxyethoxy]quinazolin-4-amine hydrochloride

Smiles: Cl.[2H]C([2H])([2H])OCCOC1=CC2=NC=NC(NC3=CC(=CC=C3)C#C)=C2C=C1OCCOC([2H])([2H])[2H]

InChiKey: GTTBEUCJPZQMDZ-HVTBMTIBSA-N

InChi: InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H/i2D3,3D3;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997 Nov 1;57(21):4838-48.

Products are for research use only. Not for human use.

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