Catalog No. Size PriceQuantity
M12256-2 2mg solid $190
M12256-10 10mg solid $645


MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM.

Product information

CAS Number: 229002-10-2

Molecular Weight: 365.43

Formula: C20H23N5O2

Chemical Name: 3-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-1-[4-(pyridin-4-yloxy)phenyl]urea

Smiles: CN1N=C(C=C1NC(=O)NC1C=CC(=CC=1)OC1C=CN=CC=1)C(C)(C)C


InChi: InChI=1S/C20H23N5O2/c1-20(2,3)17-13-18(25(4)24-17)23-19(26)22-14-5-7-15(8-6-14)27-16-9-11-21-12-10-16/h5-13H,1-4H3,(H2,22,23,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 250 mg/mL (684.13 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MPAK13-IN-1 exhibits an IC50 of 4.63 μM in vero E6 cells.


  1. Yurtsever Z, et al. First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2335-2344.
  2. Mehdi Bouhaddou, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 Aug 6;182(3):685-712.e19.

Products are for research use only. Not for human use.

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