Licochalcone E


Catalog No. Size PriceQuantity
M12259-2 2mg solid $440
M12259-10 10mg solid $1,760

Description

Licochalcone E, a flavonoid compound isolated from Glycyrrhiza inflate, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation.

Product information

CAS Number: 864232-34-8

Molecular Weight: 338.40

Formula: C21H22O4

Chemical Name: (2E)-3-{4-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl]phenyl}-1-(4-hydroxyphenyl)prop-2-en-1-one

Smiles: CC(=C)[C@H](C)C1=CC(/C=C/C(=O)C2C=CC(O)=CC=2)=C(C=C1O)OC

InChiKey: SWPKMTGYQGHLJS-RNVIBTMRSA-N

InChi: InChI=1S/C21H22O4/c1-13(2)14(3)18-11-16(21(25-4)12-20(18)24)7-10-19(23)15-5-8-17(22)9-6-15/h5-12,14,22,24H,1H2,2-4H3/b10-7+/t14-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (147.75 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed