JIP-1(153-163) TFA


Catalog No. Size PriceQuantity
M12306-2 Contact sales@xcessbio.com for quotation $100
M12306-10 Contact sales@xcessbio.com for quotation $100

Description

JIP-1(153-163) TFA (TI-JIP TFA) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide).

Product information

Molecular Weight: 1455.63

Formula: C63H105F3N20O16

Synonym:

T1-JIP TFA

Chemical Name: (S)-N1-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-2-((S)-2-((2S, 3R)-2-((2S, 3R)-2-((S)-1-((S)-2-((S)-6-amino-2-((S)-1-((S)-2-amino-5-(diaminomethyleneamino)pentanoyl)pyrrolidine-2-carboxamido)hexanamido)-5-(diaminomethyleneamino)pentanoyl)pyrrolidine-2-carboxamido)-3-hydroxybutanamido)-3-hydroxybutanamido)-4-methylpentanamido)succinamide 2, 2, 2-trifluoroacetate

Smiles: CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC1C=CC=CC=1)C(N)=O.OC(=O)C(F)(F)F

InChiKey: KJGJEJHHWVTPNI-FIMGTQIISA-N

InChi: InChI=1S/C61H104N20O14.C2HF3O2/c1-32(2)28-41(51(87)74-40(49(65)85)30-36-16-8-7-9-17-36)75-53(89)43(31-46(64)84)76-52(88)42(29-33(3)4)77-56(92)47(34(5)82)79-57(93)48(35(6)83)78-55(91)45-22-15-27-81(45)59(95)39(20-13-25-71-61(68)69)73-50(86)38(19-10-11-23-62)72-54(90)44-21-14-26-80(44)58(94)37(63)18-12-24-70-60(66)67;3-2(4,5)1(6)7/h7-9,16-17,32-35,37-45,47-48,82-83H,10-15,18-31,62-63H2,1-6H3,(H2,64,84)(H2,65,85)(H,72,90)(H,73,86)(H,74,87)(H,75,89)(H,76,88)(H,77,92)(H,78,91)(H,79,93)(H4,66,67,70)(H4,68,69,71);(H,6,7)/t34-,35-,37+,38+,39+,40+,41+,42+,43+,44+,45+,47+,48+;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Renae K Barr, et al. Identification of the critical features of a small peptide inhibitor of JNK activity. J Biol Chem. 2002 Mar 29;277(13):10987-97.

Products are for research use only. Not for human use.

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