Description
Raf inhibitor 2 is a potent raf kinase (IC50<1.0 μM) inhibitor, compound 32, extracted from patent EP1003721B1. Raf inhibitor 2 can be used for cancer research.
Product information
CAS Number: 220904-99-4
Molecular Weight: 429.49
Formula: C15H8Br2ClNO2
Chemical Name: (3Z)-5-chloro-3-[(3, 5-dibromo-4-hydroxyphenyl)methylidene]-2, 3-dihydro-1H-indol-2-one
Smiles: OC1C(Br)=CC(=CC=1Br)/C=C1\C(=O)NC2=CC=C(Cl)C=C2\1
InChiKey: MPIHOJMBMIMKAJ-KMKOMSMNSA-N
InChi: InChI=1S/C15H8Br2ClNO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (232.83 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- German, et al. Benzylidene-1,3-dihydro-indol-2-one derivatives as receptor tyrosine kinase inhibitors, particularly of raf kinases. patent/EP1003721B1
Products are for research use only. Not for human use.
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