Sorafenib (D4)

Catalog No. Size PriceQuantity
M12314-2 Contact for quotation $100
M12314-10 Contact for quotation $100


Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.

Product information

CAS Number: 1207560-07-3

Molecular Weight: 468.85

Formula: C21H16ClF3N4O3


Bay 43-9006 (D4)

Chemical Name: 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)(2, 3, 5, 6-H)phenoxy]-N-methylpyridine-2-carboxamide

Smiles: [2H]C1=C(OC2=CC(=NC=C2)C(=O)NC)C([2H])=C([2H])C(NC(=O)NC2=CC(=C(Cl)C=C2)C(F)(F)F)=C1[2H]


InChi: InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)/i2D,3D,5D,6D

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109.

Products are for research use only. Not for human use.

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