Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
CAS Number: 5578-73-4
Molecular Weight: 367.78
Chemical Name: 24-methyl-5, 7, 18, 20-tetraoxa-24-azahexacyclo[184.108.40.206, .0, .0, .0, ]tetracosa-1, 3, 8, 10, 12, 14, 16, 21, 23-nonaen-24-ium chloride
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
- Han MH, et al.Toxicol Lett. 2013 Jul 4;220(2):157-66.
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