Description
Citicoline sodium salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects.
Product information
CAS Number: 33818-15-4
Molecular Weight: 510.31
Formula: C14H25N4NaO11P2
Synonym:
Cytidine diphosphate-choline sodium
CDP-Choline sodium
Cytidine 5'-diphosphocholine sodium
Chemical Name: 2-(trimethylazaniumyl)ethyl [({[(2R, 3S, 4R, 5R)-5-(4-amino-2-oxo-1, 2-dihydropyrimidin-1-yl)-3, 4-dihydroxyoxolan-2-yl]methoxy}(sodiooxy)phosphoryl)oxy]phosphonate
Smiles: C[N+](C)(C)CCOP([O-])(=O)OP(=O)(O[Na])OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(N)=NC1=O
InChiKey: YWAFNFGRBBBSPD-OCMLZEEQSA-M
InChi: InChI=1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9-,11-,12-,13-;/m1./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : ≥ 100 mg/mL (195.96 mM) DMSO : 1 mg/mL (1.96 mM; ultrasonic and warming and heat to 80°C)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Davinelli S, et al. Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells. Oxid Med Cell Longev. 2017;2017:2825703.
- Karpova MN, et al. Increase of the seizure threshold in C57BL/6 mice after citicoline administration. Bull Exp Biol Med. 2015 Jan;158(3):315-7.
Products are for research use only. Not for human use.
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