Procyanidin C1


Catalog No. Size PriceQuantity
M12574-2 2mg solid $500
M12574-10 10mg solid $2,000

Description

Procyanidin C1 is a natural polyphenol, causes DNA damage, cell cycle arrest, and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells.

Product information

CAS Number: 37064-30-5

Molecular Weight: 866.77

Formula: C45H38O18

Chemical Name: (2R, 3R, 4S)-2-(3, 4-dihydroxyphenyl)-8-[(2R, 3R, 4R)-2-(3, 4-dihydroxyphenyl)-3, 5, 7-trihydroxy-3, 4-dihydro-2H-1-benzopyran-4-yl]-4-[(2R, 3R)-2-(3, 4-dihydroxyphenyl)-3, 5, 7-trihydroxy-3, 4-dihydro-2H-1-benzopyran-8-yl]-3, 4-dihydro-2H-1-benzopyran-3, 5, 7-triol

Smiles: OC1C=C2O[C@@H]([C@H](O)[C@@H](C3=C4O[C@@H]([C@H](O)[C@H](C4=C(O)C=C3O)C3=C4O[C@@H]([C@H](O)CC4=C(O)C=C3O)C3=CC(O)=C(O)C=C3)C3=CC(O)=C(O)C=C3)C2=C(O)C=1)C1=CC(O)=C(O)C=C1

InChiKey: MOJZMWJRUKIQGL-XILRTYJMSA-N

InChi: InChI=1S/C45H38O18/c46-18-10-27(54)33-32(11-18)61-42(16-2-5-21(48)25(52)8-16)39(59)37(33)35-29(56)14-30(57)36-38(40(60)43(63-45(35)36)17-3-6-22(49)26(53)9-17)34-28(55)13-23(50)19-12-31(58)41(62-44(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,31,37-43,46-60H,12H2/t31-,37-,38+,39-,40-,41-,42-,43-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (115.37 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Koteswari LL, et al. A comparative anticancer study on procyanidin C1 against receptor positive and receptor negative breast cancer. Nat Prod Res. 2019 Jan 8:1-8.

Products are for research use only. Not for human use.

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