Glyphosate


Catalog No. Size PriceQuantity
M12598-2 2mg solid $80
M12598-10 10mg solid $240

Description

Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants.

Product information

CAS Number: 1071-83-6

Molecular Weight: 169.07

Formula: C3H8NO5P

Chemical Name: 2-[(phosphonomethyl)amino]acetic acid

Smiles: OC(=O)CNCP(O)(O)=O

InChiKey: XDDAORKBJWWYJS-UHFFFAOYSA-N

InChi: InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 13.89 mg/mL (82.16 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Glyphosate is a high-efficiency, low-toxicity, broad-spectrum herbicide. The residues of glyphosate-based herbicides are frequent pollutants in the environment. Glyphosate exposure could interfere with mouse oocyte maturation by generating oxidative stress and early apoptosis.Glyphosate induces early apoptosis and autophagy in mouse oocytes.

References:

  1. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208.
  2. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec;237:124435.

Products are for research use only. Not for human use.

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