Description
Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants.
Product information
CAS Number: 1071-83-6
Molecular Weight: 169.07
Formula: C3H8NO5P
Chemical Name: 2-[(phosphonomethyl)amino]acetic acid
Smiles: OC(=O)CNCP(O)(O)=O
InChiKey: XDDAORKBJWWYJS-UHFFFAOYSA-N
InChi: InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 13.89 mg/mL (82.16 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Glyphosate is a high-efficiency, low-toxicity, broad-spectrum herbicide. The residues of glyphosate-based herbicides are frequent pollutants in the environment. Glyphosate exposure could interfere with mouse oocyte maturation by generating oxidative stress and early apoptosis.Glyphosate induces early apoptosis and autophagy in mouse oocytes.
References:
- Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208.
- Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec;237:124435.
Products are for research use only. Not for human use.
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