Description
Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs.
Product information
CAS Number: 4672-49-5
Molecular Weight: 218.25
Formula: C4H10O6S2
Chemical Name: 2-(methanesulfonyloxy)ethyl methanesulfonate
Smiles: CS(=O)(=O)OCCOS(C)(=O)=O
InChiKey: QSQFARNGNIZGAW-UHFFFAOYSA-N
InChi: InChI=1S/C4H10O6S2/c1-11(5,6)9-3-4-10-12(2,7)8/h3-4H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (458.19 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Ethylene dimethanesulfonate (subcutaneous injection; 75 mg/kg; 7 days) disrupts epididymal function and leads to sperm granuloma formation in rat.
References:
- Dutta D, et al. Ethylene dimethane sulfonate (EDS) ablation of Leydig cells in adult rat depletes testosterone resulting in epididymal sperm granuloma: Testosterone replacement prevents granuloma formation. Reprod Biol. 2019 Mar;19(1):89-99.
Products are for research use only. Not for human use.
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