3-Dehydrotrametenolic acid


Catalog No. Size PriceQuantity
M12630-2 2mg solid $245
M12630-10 10mg solid $930

Description

3-​Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-​Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-​Dehydrotrametenolic acid induces apoptosis and has anticancer activity.

Product information

CAS Number: 29220-16-4

Molecular Weight: 454.68

Formula: C30H46O3

Chemical Name: (2R)-2-[(1R, 3aR, 5aR, 7S, 9aS, 11aR)-7-hydroxy-3a, 6, 6, 9a, 11a-pentamethyl-1H, 2H, 3H, 3aH, 5H, 5aH, 6H, 7H, 8H, 9H, 9aH, 11H, 11aH-cyclopenta[a]phenanthren-1-yl]-6-methylhept-5-enoic acid

Smiles: CC1(C)[C@@H]2CC=C3C(=CC[C@]4(C)[C@H](CC[C@]43C)[C@@H](CCC=C(C)C)C(O)=O)[C@@]2(C)CC[C@@H]1O

InChiKey: QFPLAAZRZNKRRY-GIICLEHTSA-N

InChi: InChI=1S/C30H46O3/c1-19(2)9-8-10-20(26(32)33)21-13-17-30(7)23-11-12-24-27(3,4)25(31)15-16-28(24,5)22(23)14-18-29(21,30)6/h9,11,14,20-21,24-25,31H,8,10,12-13,15-18H2,1-7H3,(H,32,33)/t20-,21-,24+,25+,28-,29-,30+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86.
  2. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.

Products are for research use only. Not for human use.

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