Mcl1-IN-4


Catalog No. Size PriceQuantity
M12749-2 Contact sales@xcessbio.com for quotation $100
M12749-10 Contact sales@xcessbio.com for quotation $100

Description

Mcl1-IN-4 is an inhibitor of Mcl1 with an IC50 of 0.2 μM.

Product information

CAS Number: 1580484-04-3

Molecular Weight: 502.58

Formula: C28H26N2O5S

Chemical Name: 4-(4-methylnaphthalen-1-yl)-2-[3-(morpholin-4-yl)benzenesulfonamido]benzoic acid

Smiles: CC1=CC=C(C2=CC=CC=C21)C1=CC(NS(=O)(=O)C2=CC(=CC=C2)N2CCOCC2)=C(C=C1)C(O)=O

InChiKey: QFWAEPBEJCIANQ-UHFFFAOYSA-N

InChi: InChI=1S/C28H26N2O5S/c1-19-9-11-24(25-8-3-2-7-23(19)25)20-10-12-26(28(31)32)27(17-20)29-36(33,34)22-6-4-5-21(18-22)30-13-15-35-16-14-30/h2-12,17-18,29H,13-16H2,1H3,(H,31,32)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Mcl1-IN-4 is compound 19.

References:

  1. Petros A, et al. Fragment-based Discovery of Potent Inhibitors of the Anti-Apoptotic MCL-1 Protein. Bioorg Med Chem Lett, 24 (6), 1484-1488.

Products are for research use only. Not for human use.

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