NY2267


Catalog No. Size PriceQuantity
M12762-2 2mg solid $170
M12762-10 10mg solid $555

Description

NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation.

Product information

CAS Number: 886053-73-2

Molecular Weight: 637.76

Formula: C38H43N3O6

Chemical Name: tert-butyl 2-({6-[(cyclohexylcarbamoyl)({N-[(4-methoxyphenyl)methyl]-1-(pyridin-2-yl)formamido})methyl]naphthalen-2-yl}oxy)acetate

Smiles: COC1C=CC(CN(C(C2=CC3=CC=C(C=C3C=C2)OCC(=O)OC(C)(C)C)C(=O)NC2CCCCC2)C(=O)C2=CC=CC=N2)=CC=1

InChiKey: RVGDACCXDZIPOB-UHFFFAOYSA-N

InChi: InChI=1S/C38H43N3O6/c1-38(2,3)47-34(42)25-46-32-20-17-27-22-29(16-15-28(27)23-32)35(36(43)40-30-10-6-5-7-11-30)41(37(44)33-12-8-9-21-39-33)24-26-13-18-31(45-4)19-14-26/h8-9,12-23,30,35H,5-7,10-11,24-25H2,1-4H3,(H,40,43)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (392.00 mM; Need ultrasonic and warming)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

NY2267 strongly inhibits oncogenic transformation induced by Myc.

References:

  1. Yang Xu,et al. A credit-card library approach for disrupting protein-protein interactions. Bioorg Med Chem. 2006 Apr 15;14(8):2660-73.

Products are for research use only. Not for human use.

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