Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production.
CAS Number: 1185-57-5
Molecular Weight: 261.98
Ammonium ferric citrate
Chemical Name: azane;2-hydroxypropane-1, 2, 3-tricarboxylate;iron(3+)
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 33.33 mg/mL (Need ultrasonic) DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter. Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L.
- Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.
- Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625.
Products are for research use only. Not for human use.
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