Pioglitazone D4


Catalog No. Size PriceQuantity
M12796-2 2mg solid $1,145
M12796-10 10mg solid $4,580

Description

Pioglitazone D4 (U 72107 D4) is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.

Product information

CAS Number: 1134163-29-3

Molecular Weight: 360.46

Formula: C19H20N2O3S

Synonym:

U 72107 D4

Chemical Name: 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy](2, 3, 5, 6-H)phenyl}methyl)-1, 3-thiazolidine-2, 4-dione

Smiles: [2H]C1=C(OCCC2=CC=C(CC)C=N2)C([2H])=C([2H])C(CC2SC(=O)NC2=O)=C1[2H]

InChiKey: HYAFETHFCAUJAY-YBNXMSKUSA-N

InChi: InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)/i4D,5D,7D,8D

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Kuwabara K, et al. A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose leve

Products are for research use only. Not for human use.

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