(+)-Nortrachelogenin


Catalog No. Size PriceQuantity
M12899-2 Contact sales@xcessbio.com for price quotation $100
M12899-10 Contact sales@xcessbio.com for price quotation $100

Description

(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity.

Product information

CAS Number: 61521-74-2

Molecular Weight: 374.38

Formula: C20H22O7

Synonym:

Wikstromol

Chemical Name: (+)-Nortrachelogenin

Smiles: COC1C=C(C[C@@H]2COC(=O)[C@@]2(O)CC2C=C(OC)C(O)=CC=2)C=CC=1O

InChiKey: ZITBJWXLODLDRH-JLTOFOAXSA-N

InChi: InChI=1S/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-11-27-19(23)20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Wikstromol induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway.

References:

  1. A Kato,et al. (+)-Nortrachelogenin, A New Pharmacologically Active Lignan From Wikstroemia indica. J Nat Prod. 1979 Mar;42(2):159-162.
  2. Huankai Yao, et al. Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway.

Products are for research use only. Not for human use.

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