Edaravone D5


Catalog No. Size PriceQuantity
M12911-2 Contact sales@xcessbio.com for quotation $100
M12911-10 Contact sales@xcessbio.com for quotation $100

Description

Edaravone D5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.

Product information

CAS Number: 1228765-67-0

Molecular Weight: 179.23

Formula: C10H10N2O

Synonym:

MCI-186 D5

Chemical Name: 3-methyl-1-[(2, 3, 4, 5, 6-H)phenyl]-4, 5-dihydro-1H-pyrazol-5-one

Smiles: [2H]C1=C(C([2H])=C([2H])C([2H])=C1[2H])N1N=C(C)CC1=O

InChiKey: QELUYTUMUWHWMC-VIQYUKPQSA-N

InChi: InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3/i2D,3D,4D,5D,6D

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12(1): p. 9-20.
  2. Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013.
  3. Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print]

Products are for research use only. Not for human use.

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