Tamoxifen-d5


Catalog No. Size PriceQuantity
M12918-2 Contact sales@xcessbio.com for quotation $100
M12918-10 Contact sales@xcessbio.com for quotation $100

Description

Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity.

Product information

CAS Number: 157698-32-3

Molecular Weight: 376.55

Formula: C26H29NO

Synonym:

ICI 47699-​d5

(Z)-Tamoxifen-​d5

trans-Tamoxifen-​d5

Chemical Name: (2-{4-[(1Z)-1, 2-diphenyl(3, 3, 4, 4, 4-H)but-1-en-1-yl]phenoxy}ethyl)dimethylamine

Smiles: [2H]C([2H])([2H])C([2H])([2H])/C(=C(\C1C=CC=CC=1)/C1C=CC(=CC=1)OCCN(C)C)/C1C=CC=CC=1

InChiKey: NKANXQFJJICGDU-FUYVPVGLSA-N

InChi: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-/i1D3,4D2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998 Nov 26;339(22):1609-18.
  2. Zhao R, et al. Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. PLoS One. 2010 Apr 1;5(4):e9934.

Products are for research use only. Not for human use.

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