IM-250


Catalog No. Size PriceQuantity
M12924-2 2 mg solid $330
M12924-10 10 mg solid $1,165
M12924-100 100 mg solid $8,325
M12924-C Contact sales@xcessbio.com for quotation $100

Description

IM-250 not only reduces the duration of disease symptoms or time to healing but also prevents recurrent disease in guinea pigs. Treatment of recurrent infections reduces the frequency of recurrences and viral shedding, and, unlike nucleosidic drugs, IM-250 remains effective for a time after cessation of treatment. Hence, IM-250 has advantages over standard-of-care therapies and represents a promising therapeutic for chronic HSV infection, including nucleoside-resistant HSV.

Product information

CAS Number: 2305750-23-4

Molecular Weight: 435.51

Formula: C20H19F2N3O2S2

Chemical Name: (S)-2-(2',5'-difluoro-[1,1'-biphenyl]-4-yl)-N-methyl-N-(4-methyl-5-(S-methylsulfon-imidoyl)thiazol-2-yl)acetamide

Smiles: CC1N=C(SC=1[S@@](C)(=N)=O)N(C)C(=O)CC1C=CC(=CC=1)C1=CC(F)=CC=C1F

InChiKey: JDZTWDISDHLKCR-LJAQVGFWSA-N

InChi: InChI=1S/C20H19F2N3O2S2/c1-12-19(29(3,23)27)28-20(24-12)25(2)18(26)10-13-4-6-14(7-5-13)16-11-15(21)8-9-17(16)22/h4-9,11,23H,10H2,1-3H3/t29-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Gege C, Bravo FJ, Uhlig N, et al. A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections. Sci Transl Med. 2021;13(598):eabf8668.

Products are for research use only. Not for human use.

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