Description
Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca2+-activated K+ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle.
Product information
CAS Number: 12771-72-1
Molecular Weight: 450.33
Formula: C20H24BrN3O4
Chemical Name: 4-methyl-4-{2-[1-(4-nitrophenyl)-N-phenylformamido]ethyl}morpholin-4-ium bromide
Smiles: [Br-].C[N+]1(CCN(C2C=CC=CC=2)C(=O)C2C=CC(=CC=2)[N+]([O-])=O)CCOCC1
InChiKey: ZYWNKZCNUIBCSJ-UHFFFAOYSA-M
InChi: InChI=1S/C20H24N3O4.BrH/c1-23(13-15-27-16-14-23)12-11-21(18-5-3-2-4-6-18)20(24)17-7-9-19(10-8-17)22(25)26;/h2-10H,11-16H2,1H3;1H/q+1;/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Luciane M. Kawashima, et al. The development of an analytical method for two mycotoxins, patulin and verruculogen, and survey of their presence in commercial tomato pulp. Brazilian Journal of Microbiology
- Knaus HG, et al. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 1994 May 17;33(19):5819-28.
- Cui CB, et al. Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures. J Antibiot (Tokyo). 1996 Jun;49(6):534-40.
Products are for research use only. Not for human use.
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