Verubulin


Catalog No. Size PriceQuantity
M13025-2 Contact sales@xcessbio.com for quotation $100
M13025-10 Contact sales@xcessbio.com for quotation $100

Description

Verubulin (MPC-6827), a microtubule-disrupting agent with potent and broad-spectrum cytotoxic activities, acts as a promising candidate for the treatment of multiple cancer types.

Product information

CAS Number: 827031-83-4

Molecular Weight: 279.34

Formula: C17H17N3O

Chemical Name: N-(4-methoxyphenyl)-N, 2-dimethylquinazolin-4-amine

Smiles: CC1N=C(C2=CC=CC=C2N=1)N(C)C1C=CC(=CC=1)OC

InChiKey: SNHCRNMVYDHVDT-UHFFFAOYSA-N

InChi: InChI=1S/C17H17N3O/c1-12-18-16-7-5-4-6-15(16)17(19-12)20(2)13-8-10-14(21-3)11-9-13/h4-11H,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 125 mg/mL (447.48 mM), Need ultrasonic

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Sirisoma N, et al. Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration. J Med Chem. 2009 Apr 23;52(8):2341-51.
  2. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71.

Products are for research use only. Not for human use.

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