Br-PEG4-C2-Boc


Catalog No. Size PriceQuantity
M13089-2 2mg solid $80
M13089-10 10mg solid $240

Description

Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 564476-32-0

Molecular Weight: 385.29

Formula: C15H29BrO6

Chemical Name: tert-butyl 1-bromo-3,6,9,12-tetraoxapentadecan-15-oate

Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCBr

InChiKey: WLKHUFASPMJBHB-UHFFFAOYSA-N

InChi: InChI=1S/C15H29BrO6/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h4-13H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

References:

  1. Robert Yongxin Zhao, et al. Cytotoxic agents. WO2003068144A2.

Products are for research use only. Not for human use.

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