Catalog No. Size PriceQuantity
M13107-2 Contact for quotation $100
M13107-10 Contact for quotation $100


SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.

Product information

CAS Number: 115607-61-9

Molecular Weight: 334.41

Formula: C21H22N2O2

Chemical Name: 1-{8-methoxy-4-[(2-methylphenyl)amino]quinolin-3-yl}butan-1-one

Smiles: CC1=CC=CC=C1NC1C2=CC=CC(OC)=C2N=CC=1C(=O)CCC


InChi: InChI=1S/C21H22N2O2/c1-4-8-18(24)16-13-22-21-15(10-7-12-19(21)25-3)20(16)23-17-11-6-5-9-14(17)2/h5-7,9-13H,4,8H2,1-3H3,(H,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

SKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl.


  1. Keeling DJ, et al. SK&F 96067 is a reversible, lumenally acting inhibitor of the gastric (H+ + K+)-ATPase. Biochem Pharmacol. 1991 Jun 21;42(1):123-30.

Products are for research use only. Not for human use.

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