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M13118-2 Contact sales@xcessbio.com for quotation $100
M13118-10 Contact sales@xcessbio.com for quotation $100


NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM.

Product information

CAS Number: 307986-98-7

Molecular Weight: 573.67

Formula: C29H31N7O4S

Chemical Name: 4-{[3-(4-cyclohexylphenyl)[(3-methanesulfonylphenyl)carbamoyl]amino]methyl}-N-(1H-1,2,3,4-tetrazol-5-yl)benzamide

Smiles: CS(=O)(=O)C1=CC(=CC=C1)NC(=O)N(CC1C=CC(=CC=1)C(=O)NC1NN=NN=1)C1C=CC(=CC=1)C1CCCCC1


InChi: InChI=1S/C29H31N7O4S/c1-41(39,40)26-9-5-8-24(18-26)30-29(38)36(25-16-14-22(15-17-25)21-6-3-2-4-7-21)19-20-10-12-23(13-11-20)27(37)31-28-32-34-35-33-28/h5,8-18,21H,2-4,6-7,19H2,1H3,(H,30,38)(H2,31,32,33,34,35,37)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (435.79 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264.

Products are for research use only. Not for human use.

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