Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH


Catalog No. Size PriceQuantity
M13141-2 2mg solid $115
M13141-10 10mg solid $345

Description

Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET).

Product information

CAS Number: 131287-39-3

Molecular Weight: 683.66

Formula: C33H37N3O13

Synonym:

Fmoc-Asn(Ac3AcNH-beta-Glc)-OH

Chemical Name: (2S)-3-{[(2R,3R,4R,5S,6R)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]carbamoyl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

Smiles: CC(=O)N[C@H]1[C@H](NC(=O)C[C@H](NC(=O)OCC2C3=CC=CC=C3C3=CC=CC=C32)C(O)=O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChiKey: QOACISSHGAAMLK-MJCYOTSPSA-N

InChi: InChI=1S/C33H37N3O13/c1-16(37)34-28-30(48-19(4)40)29(47-18(3)39)26(15-45-17(2)38)49-31(28)36-27(41)13-25(32(42)43)35-33(44)46-14-24-22-11-7-5-9-20(22)21-10-6-8-12-23(21)24/h5-12,24-26,28-31H,13-15H2,1-4H3,(H,34,37)(H,35,44)(H,36,41)(H,42,43)/t25-,26+,28+,29+,30+,31+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (365.68 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Wängler C, et al. One-step ¹⁸F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET). Bioconjug Chem. 2010;21(12):2289-2296.

Products are for research use only. Not for human use.

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