Description
TP-472N is a negative control probe for TP-472. TP-472 is a potent and selective BRD7/9 probe.
Product information
CAS Number: 2080306-24-5
Molecular Weight: 306.36
Formula: C19H18N2O2
Chemical Name: 1-{8-[2-(cyclopropylmethoxy)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl}ethan-1-one
Smiles: CC(=O)C1=CC(=C2N=CC=CN12)C1=CC=CC=C1OCC1CC1
InChiKey: IDQWBZAMTQTECP-UHFFFAOYSA-N
InChi: InChI=1S/C19H18N2O2/c1-13(22)17-11-16(19-20-9-4-10-21(17)19)15-5-2-3-6-18(15)23-12-14-7-8-14/h2-6,9-11,14H,7-8,12H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
TP-472N is inactive against BRD9 at 20 µM.
References:
- Michael A Clegg, et al. Advancements in the Development of non-BET Bromodomain Chemical Probes. ChemMedChem. 2019 Feb 19;14(4):362-385.
Products are for research use only. Not for human use.
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