Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
CAS Number: 1013921-36-2
Molecular Weight: 231.29
Chemical Name: 3,6,9,12-tetraoxapentadec-14-yn-1-amine
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Banerjee SR, et al. 111In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific MembraneAntigen-Expressing Tissues. Biomacromolecules. 2017 Jan 9;18(1):201-209.
Products are for research use only. Not for human use.
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