MK-7622


Catalog No. Size PriceQuantity
M13184-2 Contact sales@xcessbio.com for quotation $100
M13184-10 Contact sales@xcessbio.com for quotation $100

Description

MK-7622 (M1 receptor modulator) is a muscarinic M1 receptor positive allosteric modulator.

Product information

CAS Number: 1227923-29-6

Molecular Weight: 399.48

Formula: C25H25N3O2

Chemical Name: 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]-3H,4H-benzo[h]quinazolin-4-one

Smiles: CC1=CC=C(CC2=CC3=C(N=CN([C@H]4CCCC[C@@H]4O)C3=O)C3=CC=CC=C23)C=N1

InChiKey: JUVQLZBJFOGEEO-GOTSBHOMSA-N

InChi: InChI=1S/C25H25N3O2/c1-16-10-11-17(14-26-16)12-18-13-21-24(20-7-3-2-6-19(18)20)27-15-28(25(21)30)22-8-4-5-9-23(22)29/h2-3,6-7,10-11,13-15,22-23,29H,4-5,8-9,12H2,1H3/t22-,23-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (250.33 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Kuduk Scott D, et al. Benzoquinazolinone derivatives as M1 receptor positive allosteric modulators and their preparation, pharmaceutical compositions and use in the treatment of diseases. From PCT Int. Appl. (2010), WO 2010059773 A1 20100527.

Products are for research use only. Not for human use.

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