Description
m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 215181-61-6
Molecular Weight: 145.16
Formula: C5H11N3O2
Chemical Name: 1-azido-2-(2-methoxyethoxy)ethane
Smiles: COCCOCCN=[N+]=[N-]
InChiKey: OXDZFVNIVMSPEG-UHFFFAOYSA-N
InChi: InChI=1S/C5H11N3O2/c1-9-4-5-10-3-2-7-8-6/h2-5H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References:
- Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.