Pinoresinol dimethyl ether


Catalog No. Size PriceQuantity
M13212-2 Contact sales@xcessbio.com for quotation $100
M13212-10 Contact sales@xcessbio.com for quotation $100

Description

Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furofuran lignan isolated from the stem bark of Magnolia kobus with neuritogenic activity. Pinoresinol dimethyl ether ((+)-Eudesmin) can induce neuritis outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways.

Product information

CAS Number: 29106-36-3

Molecular Weight: 386.44

Formula: C22H26O6

Synonym:

(+)-Eudesmin

Chemical Name: (1S,3aR,4S,6aR)-1,4-bis(3,4-dimethoxyphenyl)-3a,6a-dihydrogenio-hexahydrofuro[3,4-c]furan

Smiles: COC1=CC=C(C=C1OC)[C@H]1OC[C@@H]2[C@H](OC[C@@H]21)C1C=C(OC)C(=CC=1)OC

InChiKey: PEUUVVGQIVMSAW-RZTYQLBFSA-N

InChi: InChI=1S/C22H26O6/c1-23-17-7-5-13(9-19(17)25-3)21-15-11-28-22(16(15)12-27-21)14-6-8-18(24-2)20(10-14)26-4/h5-10,15-16,21-22H,11-12H2,1-4H3/t15-,16-,21+,22+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. TeruhisaMiyauchi, et al. Formation of (+)-eudesmin in Magnolia kobus DC. Var. borealis sarg. Phytochemistry, 1998, 47(4): 665-670.
  2. Yang YJ, et al. Effects of (+)-eudesmin from the stem bark of magnolia kobus DC. var. borealis Sarg. on neurite outgrowth in PC12 cells. Arch Pharm Res. 2006 Dec;29(12):1114-8.

Products are for research use only. Not for human use.

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