AZD-6280


Catalog No. Size PriceQuantity
M13219-2 2mg solid $105
M13219-10 10mg solid $315

Description

AZD-6280 is a selective GABAA(α2/3) receptor modulator, used for treatment of generalized anxiety disorder.

Product information

CAS Number: 942436-93-3

Molecular Weight: 366.41

Formula: C20H22N4O3

Chemical Name: 4-amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboxamide

Smiles: CCCNC(=O)C1=NN=C2C(=CC=CC2=C1N)C1=CC(=CC=C1OC)OC

InChiKey: NVWCZRPXYVDQEE-UHFFFAOYSA-N

InChi: InChI=1S/C20H22N4O3/c1-4-10-22-20(25)19-17(21)14-7-5-6-13(18(14)23-24-19)15-11-12(26-2)8-9-16(15)27-3/h5-9,11H,4,10H2,1-3H3,(H2,21,23)(H,22,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 62.5 mg/mL (170.57 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Te Beek E T , Chen X , Jacobs G E , et al. The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.[J]. Clin Pharmacol Drug Dev, 2015, 4(2):149-154.

Products are for research use only. Not for human use.

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