ICI 89406


Catalog No. Size PriceQuantity
M13291-2 Contact sales@xcessbio.com for quotation $100
M13291-10 Contact sales@xcessbio.com for quotation $100

Description

ICI 89406 is a selective β1 adrenergic receptor antagonist amenable to labelling with positron emitters, for PET.

Product information

CAS Number: 53671-71-9

Molecular Weight: 354.40

Formula: C19H22N4O3

Chemical Name: 1-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-3-phenylurea

Smiles: N#CC1=CC=CC=C1OCC(O)CNCCNC(=O)NC1C=CC=CC=1

InChiKey: HTLWRKRZKFAAAH-UHFFFAOYSA-N

InChi: InChI=1S/C19H22N4O3/c20-12-15-6-4-5-9-18(15)26-14-17(24)13-21-10-11-22-19(25)23-16-7-2-1-3-8-16/h1-9,17,21,24H,10-11,13-14H2,(H2,22,23,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Marilyn P Law, et al. Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET? Eur J Nucl Med Mol Imaging. 2008 Jan;35(1):174-85.
  2. B Costall, et al. Changes in dopamine receptor status after denervation or chronic receptor stimulation [proceedings]. Br J Pharmacol. 1979 Jul;66(3):492P-493P.

Products are for research use only. Not for human use.

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