Description
BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice.
Product information
CAS Number: 127299-93-8
Molecular Weight: 385.82
Formula: C19H21ClNNaO4
Synonym:
BRL 37344A
Chemical Name: sodium 2-{4-[(2S)-2-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}propyl]phenoxy}acetate
Smiles: [Na+].C[C@@H](CC1C=CC(=CC=1)OCC([O-])=O)NC[C@@H](O)C1C=C(Cl)C=CC=1
InChiKey: SNJIJYKMYQRHRC-UFRBEDTPSA-M
InChi: InChI=1S/C19H22ClNO4.Na/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);/q;+1/p-1/t13-,18+;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
BRL37344 sodium (BRL 37344A) treatment significantly lowers the body weight of obese mice.
References:
- Wu C, et al. Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. PLoS One. 2014 Dec 2;9(12):e113742.
Products are for research use only. Not for human use.
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